Handbook of Drug Metabolism (Paperback) (ISBN-13: 9780367399856)

Bringing together nearly forty collaborators from academic and industrial laboratories, this reference furnishes an overview of the subject in a historical, kinetic, and chemical context. A source of expertise for a rapidly changing and expanding field, the book provides a framework for drug metabolism in drug discovery and development. Containing tables, drawings, photographs, and equations, it highlights the importance of pharmacokinetics and cytochrome P450, explains clearance, volume of distribution, sequential metabolism, and nonlinear kinetics, summarizes concepts of Phase 1 and 2 metabolites, evaluates tertiary amine metabolism and reactive metabolite chemistry, and more.

Author: Thomas Woolf
ISBN-10: 0367399857
ISBN-13: 9780367399856
Publisher: CRC Press
Language: English
Published: 06/19/2019
Pages: 612
Format: Paperback
Weight: 2.80lbs
Size: 9.90h x 7.00w x 1.20d