Immunoreceptor Tyrosine-Based Inhibition Motifs (Paperback) (ISBN-13: 9783642636349)

Novel molecular motifs named Immunoreceptor Tyrosine-based Inhibition Motifs (ITIMs) have recently been recognized in the intracytoplasmic domains of a still-increasing number of receptors which control cell activation and proliferation. Research on ITIM-bearing molecules has developed exponentially during the last three years, generating new concepts with important consequences in basic research and with exciting potential clinical applications. The present volume contains 15 reviews written by authors who all made significant contributions to the identification of ITIM-bearing molecules and the study of their biological properties. It constitutes the first synthesis ever published that is specifically devoted to this emerging topic.

Author: Marc Daeron
ISBN-10: 3642636349
ISBN-13: 9783642636349
Publisher: Springer
Language: English
Published: 10/14/2012
Pages: 183
Format: Paperback
Weight: 0.62lbs
Size: 9.21h x 6.14w x 0.42d