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The diagnostic application of MRI Contrast agents, both in the form of Gd3+ and transition metal complexes, like Mn at different oxidation states, as well as of nanomaterials, such as iron oxides, ferrites and Ln3+ salts, including their theranostic potential, is described in detail.
Carlos F. G. C. Geraldes received his "Licenciatura" (MS equivalent) in Chemistry from the University of Coimbra in 1972, and his Doctor of Philosophy (D.Phil) degree in Inorganic Chemistry from the University of Oxford in 1976 with Prof. Robert J. P. Williams. In his graduate work, he studied the solution conformation of a series of mono and dinucleotides using the so-called Lanthanide Probe Method, measuring the proton NMR induced shifts and nuclear relaxation rates of their complexes of whole paramagnetic Ln(III) series combined with coupling constants and NOE data.
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