Lymphocyte Activation and Immune Regulation IX: Homeostasis and Lymphocyte Traffic (Hardcover) (ISBN-13: 9780306473951)

This volume is divided into three sections. Section I deals with factors that regulate the development and maturation of T cells and B cells and lymphocyte traffic. The significance of C-kit, Bcl-6, IL-7, and Vav in the development of T and B lymphocytes is discussed. A role of lymphotoxins and VAP-I in trafficking of leucocytes is reviewed. Finally, the trafficking and homing characteristics of T cell and B cell subsets, and the regulation of these processes during the immune response, is presented.
Section II discusses various aspects of naive and memory T cell biology, including clonal expansion, reprogramming of genes including those encoding cytokines and cytotoxic granules, changes in the expression of cell surface proteins involved in cell-cell adhesion, homing of naive and memory T cells, the role of MHC and cytokines in the maintenance of naive and memory T cells, and the characterization and differentiation of virus-specific memory T cell heterogeneity in mice and humans.
Novel methods of visualization of immune cells and immune systems are reviewed in Section III.

Author: Sudhir Gupta
ISBN-10: 030647395X
ISBN-13: 9780306473951
Publisher: Springer
Language: English
Published: 10/31/2002
Pages: 212
Format: Hardcover
Weight: 1.10lbs
Size: 9.21h x 6.14w x 0.56d