Mechanisms of Environmental Mutagenesis-Carcinogenesis (Hardcover) (ISBN-13: 9780306437250)

Mutations and Carcinogenicity.- Mutation Spectrum in Carcinogenicity.- Mechanisms of Chemically-Induced Genetic Effects on Molecular, Chromosomal and Cell Division Level.- Ultraviolet Light Mutagenesis in Bacteria: The Possible Role of a DNA Polymerase III Complex Lacking Proofreading Exonuclease.- Centromere Separation: Emerging Relationship with Aneuploidy.- Genetic Analysis of Genotoxic Effects on Chromosomes and Cell Division in Lower Eukaryotes.- DNA Repair and the Recombination Barrier between Divergent (Homologous) Chromosomes.- Consequences of Altering Tubulin Levels in Yeast.- A Genetic Assay Using Rodent/Human Hybrid Cells to Evaluate the Genotoxic Effects of Chemicals for Multiple Endpoints.- Aneuploidy in Humans.- Adaptability and Repair Mechanisms.- The Adaptive Response to Alkylation Damage in Escherichia coli.- The Adaptive Response of Human Lymphocytes to Radiation or Chemical Mutagens: Cross-Adaptation and Synergism.- Evolving Mutation Rates and Prospects for Antimutagenesis.- Genetic Analysis of DNA Repair Defect in Xeroderma Pigmentosum Cells: Identification of Complementing Genes.- Chemical Carcinogenesis-Oncogenes.- Outline of a Descriptive General Theory of Environmental Chemical Cancerogenesis - Experimental Threshold Doses for Tumor Promoters.- The Interaction of Steroid Hormones and Oncogenes in the Establishment of Malignancy.- The Relationship between DNA-Alkali-Labile Sites and Carcinogenesis in Mammalian Cells.- Structure and Metabolism of Mutagens-Carcinogens.- Quantitative Structure-Activity Relationships, and Mutagens and Carcinogens.- Enzymic Aspects on the Metabolic Activation of Aromatic and Heterocyclic Amine Mutagensin Mammalian and Bacterial Cells.- Biomonitoring and Epidemiology of Humans Exposed to Environmental Mutagens-Carcinogens.- Current Techniques for Human Population Monitoring for Genetic Effects.- Use of Aquatic Animals for Monitoring Genotoxicity in Unconcentrated Water Samples.- Cytogenetic Monitoring of Industrial Workers Exposed to Chemicals.- Monitoring Congenital Anomalies in Populations Exposed to Environmental Mutagens.- European Community Research on Genetic Effects of Environmental Chemicals and on Biomonitoring of Human Exposure.- Contributors.

Author: European Environmental Mutagen Society,A. Kappas,A. Ed. Kappas
ISBN-10: 0306437252
ISBN-13: 9780306437250
Publisher: Plenum Publishing Corporation
Language: English
Published: 02/01/1991
Pages: 296
Format: Hardcover
Weight: 1.61lbs
Size: 10.00h x 7.00w x 0.69d