Melanoma Techniques and Protocols: Molecular Diagnosis, Treatment, and Monitoring (Hardcover) (ISBN-13: 9780896036840)

This book is about melanoma--its biology, immunology, and pathology, as well as the initial use of powerful genomic tools to study its fundamental mole- lar and genetic characteristics. The study of cancer will be profoundly impacted by the Human Genome Project. I would like to discuss some of these changes. The first draft of the human genome sequence was announced in June 2000, and we have just scratched the surface of the changes it will engender in medicine. A relevant question is what are the long-term effects of the Human Genome Project for medicine? I would argue that there are three, and each of these three point toward the view that systems biology will dominate biology and medicine of the 21st century. First, the Human Genome Project introduced a new type of s- ence--discovery science. Discovery science takes a biological system (e. g., the genome) and defines all of its elements (e. g., the sequences of the 24 human ch- mosomes). Thus, it creates a rich infrastructure from which the classical hypo- esis-driven science can be done more effectively. The effective integration of discovery- and hypothesis-driven science is a key for systems approaches to bi- ogy and medicine. Second, the Human Genome Project has provided a "periodic table of life.

Author: Brian J. Nickoloff
ISBN-10: 0896036847
ISBN-13: 9780896036840
Publisher: Humana
Language: English
Published: 06/01/2001
Pages: 368
Format: Hardcover
Weight: 1.67lbs
Size: 9.88h x 6.36w x 0.95d

Review Citation(s):
Scitech Book News 09/01/2001 pg. 95