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Migraine and headache are highly prevalent common diseases; however, the pathogenesis of these primary headaches has not been completely revealed. Recent advances and clinical applications of CGRP blocking therapies have provided great advances for both basic and clinical research into headaches. This Special Issue has collected cutting edge original research articles, reviews and case reports of migraines and headaches. I hope this Special Issue may contribute the current understanding of migraines and headaches at large.
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