Molecular Docking Studies of Moa-B Inhibitors (Paperback) (ISBN-13: 9786208417109)

The present study was aimed at molecular docking studies of known inhibitors of MAO protein is to understand the binding interactions between the inhibitor and the enzyme at a molecular level. All Candidates from the database were selected as potential leads against MAO -B enzyme. The structural diversity has been observed in the compounds. The high affinity of the ligand Befloxatone is attributed to its four binding interactions at the active site of the protein. And other compounds also shows good binding energy. Thus, the obtained hits could be treated as good leads in the design of potent inhibitors of MAO- B enzyme, most commonly found to be expressed in the Parkinson's patients.

Author: Rahul Singh, Avinash C. Tripathi
ISBN-10: 6208417104
ISBN-13: 9786208417109
Publisher: LAP Lambert Academic Publishing
Language: English
Published: 12/17/2024
Pages: 52
Format: Paperback
Weight: 0.20lbs
Size: 9.00h x 6.00w x 0.12d