Nicotine and Related Alkaloids: Absorption, Distribution, Metabolism and Excretion (Hardcover) (ISBN-13: 9780412557408)

Plant metabolism. Mammalian metabolism: overview. Nicotine to cotinine. Nicotine to cotinine: enzyme induction. N-oxidation, N-methylation and conjugation reactions. Nicotine metabolism: beyond cotinine. Extrahepatic nicotine metabolism. Minor tobacco alkaloids. Pharmacokinetics of nicotine and metabolites in animals. Pharmacokinetics of nicotine and metabolites in humans. Factors influencing individual variation in nicotine pharmacokinetics. Analysis of nicotine. Chromatographic analysis of nicotine and metabolites. Nicotine and metabolites: pharmacokinetics models. New methods for probing the in vivo disposition of nicotine in humans. Aspects of metabolism of S- nicotine.

Author: John Wahren
ISBN-10: 0412557401
ISBN-13: 9780412557408
Publisher: Chapman & Hall
Language: English
Published: 09/30/1993
Pages: 320
Format: Hardcover
Weight: 1.38lbs
Size: 9.21h x 6.14w x 0.75d