Oral Bioavailability Assessment: Basics and Strategies for Drug Discovery and Development by El-Kattan, Ayman F.

Oral Bioavailability Assessment: Basics and Strategies for Drug Discovery and Development (Hardcover) (ISBN-13: 9781118916698)

Vendor: Ayman F. El-Kattan
Product type: Books
Format: Hardcover
$187.95
$187.95
$187.95
Subtotal: $187.95
Oral Bioavailability Assessment: Basics and Strategies for Drug Discovery and Development by El-Kattan, Ayman F.

Oral Bioavailability Assessment: Basics and Strategies for Drug Discovery and Development

$187.95
Oral Bioavailability Assessment: Basics and Strategies for Drug Discovery and Development by El-Kattan, Ayman F.

Oral Bioavailability Assessment: Basics and Strategies for Drug Discovery and Development

$187.95
Format: Hardcover
Description
Description
x
Specifically geared to personnel in the pharmaceutical and biotechnology industries, this book describes the basics and challenges of oral bioavailability - one of the most significant hurdles in drug discovery and development.

- Describes approaches to assess pharmacokinetics and how drug efflux and uptake transporters impact oral bioavailability
- Helps readers reduce the failure rate of drug candidates when transitioning from the bench to the clinic during development
- Explains how preclinical animal models - used in preclinical testing - and in vitro tools translate to humans, which is an underappreciated and complicated area of drug development
- Includes chapters about pharmacokinetic modelling, the Biopharmaceutics Drug Disposition Classification System (BDDCS), and the Extended Clearance Classification System (ECCS)
- Has tutorials for applying strategies to medicinal chemistry practices of drug discovery/development

Author: Ayman F. El-Kattan
ISBN-10: 1118916697
ISBN-13: 9781118916698
Publisher: Wiley
Language: English
Published: 06/06/2017
Pages: 448
Format: Hardcover
Weight: 1.70lbs
Size: 9.30h x 6.20w x 1.10d
By Ayman F. El-Kattan
By Ayman F. El-Kattan
x

AYMAN F. EL-KATTAN, B. Pharm, PhD, is Associate Research Fellow in Pfizer's Pharmacokinetics, Dynamics, and Metabolism Department, Cambridge Laboratories and an Adjunct Professor at College of Pharmacy-University of Rhode Island in Rhode Island, US. Dr. El-Kattan is a reviewer for several journals and is an active member of the American Association of Pharmaceutical Scientists (AAPS). He serves on the executive committee of the Drug Transporter focus group. He has been invited speaker 50 times at national/international conferences and has published over 100 papers in peer-reviewed Journals, book chapters, and proceedings.

Recently Viewed Products