Parent-of-origin Effect in Families of Bipolar Disorder by Lan, Tsuo-Hung

Parent-of-origin Effect in Families of Bipolar Disorder (Paperback) (ISBN-13: 9783639107937)

Vendor: Tsuo-Hung Lan
Product type: Books
Format: Paperback
$85.32
$85.32
$85.32
Subtotal: $85.32
Parent-of-origin Effect in Families of Bipolar Disorder by Lan, Tsuo-Hung

Parent-of-origin Effect in Families of Bipolar Disorder

$85.32
Parent-of-origin Effect in Families of Bipolar Disorder by Lan, Tsuo-Hung

Parent-of-origin Effect in Families of Bipolar Disorder

$85.32
Format: Paperback
Description
Description
x
Bipolar disorder is a chronic psychiatric disease characterized by swinging pathologic mood changes and potentially devastating impact on social functioning with an estimated 1% life prevalence in United States. Twin, adoption, and family studies have supported the role of a genetic component in the pathogenesis of bipolar disorder. In this book, three different approaches (segregation analysis, IBD analysis, and TDT analysis) were applied to test for heterogeneity between two subgroups defined by parental lineality of disease transmission. These three lines of evidence support heterogeneity of bipolar disorder between families with different parental transmission linearity. They also confirm previously suspected parent-of-origin phenomenon and suggest a possible way to enhance the prevention, diagnosis, and treatment of bipolar disorder in public health by incorporating this idea into further approaches.

Author: Tsuo-Hung Lan
ISBN-10: 3639107934
ISBN-13: 9783639107937
Publisher: VDM Verlag
Language: English
Published: 07/30/2009
Pages: 344
Format: Paperback
Weight: 1.11lbs
Size: 9.00h x 6.00w x 0.77d

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