Pathway to USMLE: Volume II - Haematology & Transfusion Medicine (Paperback) (ISBN-13: 9788168673045)

Mechanism-first haematology and transfusion medicine for USMLE Step 1 and Step 2 CK.

Volume II of the Pathway to USMLE series treats the blood and marrow as a single integrated system - from red cell membrane biology to platelet plug formation to the molecular lesions of lymphoid neoplasia. Every disease is pinned to a precise mechanism and the vignette pattern that earns the question.

What's inside

• WHO 5th edition and ICC 2022 classifications throughout - the current standards for AML, MDS, ALL, MPN, MDS/MPN, and the lymphoid neoplasms.


• Molecular diagnostics integrated chapter-by-chapter: BCR-ABL1, JAK2 V617F, FLT3-ITD, NPM1, CEBPA, IGH/MYC translocations, BCL2/BCL6 rearrangements.


• Bleeding and clotting algorithms with closing discriminators that separate look-alikes (vWD subtypes, the haemophilias, DIC vs liver failure vs TTP/HUS).


• Transfusion medicine in full clinical context: ABO/Rh, pre-transfusion testing, components and indications, transfusion reactions, TRALI vs TACO, paediatric and neonatal transfusion, apheresis, HSCT, and special transfusion topics.

Built for international medical graduates as much as US students. Every chapter pairs mechanism with morphology and clinical decision-making in a British medical voice that maps cleanly to FRCPath, PLAB, MCCQE, AMC, and NEET-PG vocabulary while staying USMLE-tight.

Chapter coverage

• Red cell disorders: microcytic, macrocytic, and haemolytic anaemias; haemoglobinopathies


• White cell disorders and reactive conditions


• Acute leukaemias (AML and ALL); chronic leukaemias and myeloproliferative neoplasms


• Lymphomas (Hodgkin and non-Hodgkin); plasma cell neoplasms


• Haemostasis and bleeding disorders; thrombosis, thrombophilia, and anticoagulation


• Transfusion medicine

333 pages, 7×10 trim. Companion to Volume I (General Pathology) and Volume III (Systemic Pathology).

About the author. Vishal Tayade is Assistant Professor of Pathology at Grant Government Medical College and Sir J.J. Group of Hospitals, Mumbai. He trained in oncopathology at Tata Memorial Centre and holds Part 1 of the FRCPath. His research and teaching span haematopathology, molecular diagnostics, and surgical pathology.