Pheochromocytoma: First International Symposium, Volume 1073 by Pacak, Karel

Pheochromocytoma: First International Symposium, Volume 1073 (Paperback) (ISBN-13: 9781573315975)

Vendor: Karel Pacak
Product type: Books
Format: Paperback
$183.00
$183.00
$183.00
Subtotal: $183.00
Pheochromocytoma: First International Symposium, Volume 1073 by Pacak, Karel

Pheochromocytoma: First International Symposium, Volume 1073

$183.00
Pheochromocytoma: First International Symposium, Volume 1073 by Pacak, Karel

Pheochromocytoma: First International Symposium, Volume 1073

$183.00
Format: Paperback
Description
Description
x
Pheochromocytoma is a rare neuroendocrine tumor with a highly variable presentation. There is lack of agreement about the most efficient and cost-effective methods for diagnosis and localization of the tumor, which can be lethal if not identified and treated promptly.Autopsy studies indicate that up to 50% of all cases remain undiagnosed until death.

Between 30 and 35% of the tumors have a hereditary basis. Development of malignancy is highly variable -- from less than 5% to more than 50% depending on the mutation; there is currently no effective cure.

This volume encompasses a number of themes in several sections: genetics and clinical decision-making; genetics, molecular pathways of tumorigenesis, and divergent phenotypes; kaleidoscopic presentations and a minefield for differential diagnosis of pheochromocytoma; biochemical diagnosis: can we reach consensus?; tumor localization and the evolving importance of functional imaging; and new molecular markers and targets for diagnosis and treatment of malignant pheochromcytoma.

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Author: Karel Pacak
ISBN-10: 1573315974
ISBN-13: 9781573315975
Publisher: Wiley-Blackwell
Language: English
Published: 08/21/2006
Pages: 328
Format: Paperback
Weight: 1.76lbs
Size: 9.10h x 6.02w x 1.29d

Review Citation(s):
Scitech Book News 12/01/2006 pg. 76
By Karel Pacak
By Karel Pacak
x

Karel Pacak is a professor who established the Pheochromocytoma Research Program at the NIH, one of the most prestigious and largest programs worldwide, and has published over 80 articles/book chapters on this topic. He has Introduced new biochemical and imaging approaches to this tumor, especially the use of 18F-fluorodopamine in localization of pheochromocytoma. He also developed new biochemical and imaging algorithms for pheochromocytoma for practicing physicians. Moreover, developed new animal model of metastatic pheochromocytoma. Currently working as the Chief of Section on Medical Neuroendocrinology, NICHD. He is also Professor of Medicine at Georgetown University, Washington DC and Charles University, Prague, Czech Republic.

Graham Eisenhofer is a clinical biochemist with broad experience in basic and patient-oriented research on neuroedocrine and autonomic nervous system function in health and disease. Relevant achievements include codevelopment with Dr. Jacques Lenders of the first HPLC method for measurements of plasma free metanephrines, a test now used for improved biochemical diagnosis of pheochromocytoma. Dr. Eisenhofer was also responsible for initial development of 18F-fluorodopamine as a positron emission tomographic imaging agent for visualizing sympathetic nerves and neuroendocrine tumors. Dr. Eisenhofer co-chairs the Pheochromocytoma RESearch Support ORganization.

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