Photodynamic Therapy: Methods and Protocols (Hardcover) (ISBN-13: 9781071620984)

Part I: In Vitro and In Vivo Models to Study Photodynamic Therapy

1. Application of Monolayer Cell Cultures for Investigating Basic Mechanisms of Photodynamic Therapy

Mans Broekgaarden

2. The Negative Impact of Cancer Cell Nitric Oxide on Photodynamic Therapy

Jonathan M. Fahey and Albert W. Girotti

3. Microtumor Models as a Preclinical Investigational Platform for Photodynamic Therapy

Mans Broekgaarden and Jean-Luc Coll

4. A Microfluidic Model to Evaluate Photodynamic Therapy Treatment Response in 3D Tumors

Shubhankar Nath, Michael Pigula, Tayyaba Hasan, and Imran Rizvi

5. Analysis of Treatment Effects on Structurally Complex Microtumor Cultures Using a Comprehensive Image Analysis Procedure

Anne-Laure Bulin, Mans Broekgaarden, and Tayyaba Hasan

6. High-Throughput Examination of Therapy-Induced Alterations in Redox Metabolism in Spheroid and Microtumor Models

Mans Broekgaarden, Anne-Laure Bulin, and Tayyaba Hasan

7. Spatiotemporal Tracking of Different Cell Populations in Cancer Organoid Models for Investigations on Photodynamic Therapy

Anne-Laure Bulin and Tayyaba Hasan

8. Generating Large Numbers of Pancreatic Microtumors on Alginate-Gelatin Hydrogels for Quantitative Imaging of Tumor Growth and Photodynamic Therapy Optimization

Nazareth Milagros Carigga Gutierrez, Tristan Le Clainche, Jean-Luc Coll, Lucie Sancey, and Mans Broekgaarden

9. The Chicken Embryo Chorioallantoic Membrane as an In Vivo Model for Photodynamic Therapy

Jaroslava Joniová and Georges Wagnières

10. Subcutaneous Xenograft Models for Studying PDT In Vivo

Girgis Obaid and Tayyaba Hasan

11. In Vivo Models for Studying Interstitial Photodynamic Therapy of Locally Advanced Cancer

Gal Shafirstein, Emily Oakley, Sasheen Hamilton, Michael Habitzruther, Sarah Chamberlain, Sandra Sexton, Leslie Curtin, and David A. Bellnier

12. Orthotopic Models of Pancreatic Cancer to Study PDT

Girgis Obaid, Zhiming Mai, and Tayyaba Hasan

13. An Orthotopic Murine Model of Peritoneal Carcinomatosis of Ovarian Origin for Intraoperative PDT

Thierry Michy, Claire Bernard, Jean Luc Coll, and Véronique Josserand

14. Photodynamic Treatments for Disseminated Cancer Metastases Using Fiber-Optic Technologies

Eric M. Kercher and Bryan Q. Spring

15. Stereotaxic Implantation of F98 Cells in Fischer Rats: A Syngeneic Model to Investigate Photodynamic Therapy Response in Glioma

Anne-Laure Bulin, Jean-François Adam, and Hélène Elleaume