Protein Misfolding Disorders: A Trip into the ER (Paperback) (ISBN-13: 9781608055753)

Neurodegenerative disorders such as Amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), Parkinson's disease (PD), Prion-related disorders (PrD) and Huntington's disease (HD) share a common neuropathology, primarily featuring the presence of abnormal protein inclusions containing specific misfolded proteins. These groups of diseases are now classified as Protein Misfolding Disorders. This book gives a comprehensive overview of the possible mechanisms involved in Protein Misfolding Disorders and possible therapeutic strategies to treat these diseases. The book provides the most recent evidence addressing the role of cellular stress responses to neurological diseases, along with therapeutic strategies to alleviate ER stress in a disease context.

Author: Claudio Hetz
ISBN-10: 1608055752
ISBN-13: 9781608055753
Publisher: Bentham Science Publishers
Language: English
Published: 02/23/2018
Pages: 156
Format: Paperback
Weight: 1.14lbs
Size: 11.00h x 8.50w x 0.41d