Sarcopenia - Age-Related Muscle Wasting and Weakness: Mechanisms and Treatments (Paperback) (ISBN-13: 9789400790445)

1.Overview.- 2. Molecular mechanisms of muscle wasting in cancer and ageing: cachexia versus sarcopenia.- 3. Age-related remodeling of neuromuscular junctions.- 4.Motor unit remodeling during aging.- 5. Age-related decline in actomyosin structure and function.- 6. Excitation-contraction coupling in aged skeletal muscle.- 7. Mitochondrial function in aging skeletal muscle.- 8. Fibrosis and skeletal muscle aging.- 9. Nuclear apoptosis and sarcopenia.- 10. Age-related changes in the molecular regulation of skeletal muscle mass.- 11. Genetic variation and skeletal muscle traits: implications for sarcopenia.- 12. Proteomic profiling of aged skeletal muscle.- 13. Aging, exercise and muscle protein metabolism.- 14. Reactive oxygen species generation and skeletal muscle wasting - implications for sarcopenia.- 15. Exercise as a countermeasure for sarcopenia.- 16. Role of contraction-induced injury in age-related muscle wasting and weakness.- 17. Role of IGF-I signaling in age-related changes in skeletal muscle.- 18. Role of myostatin and TGF-beta signaling in skeletal muscle growth and development: implications for sarcopenia.- 19. β-Adrenergic signaling in sarcopenia and other muscle wasting disorders.

Author: Gordon S. Lynch
ISBN-10: 9400790449
ISBN-13: 9789400790445
Publisher: Springer
Language: English
Published: 11/12/2014
Pages: 479
Format: Paperback
Weight: 1.52lbs
Size: 9.21h x 6.14w x 1.00d