Simulation for Designing Clinical Trials: A Pharmacokinetic-Pharmacodynamic Modeling Perspective (Hardcover) (ISBN-13: 9780824708627)

Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to clinical trial designs according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.

Author: Hui Kimko
ISBN-10: 0824708628
ISBN-13: 9780824708627
Publisher: CRC Press
Language: English
Published: 12/12/2002
Pages: 424
Format: Hardcover
Weight: 1.62lbs
Size: 9.34h x 6.32w x 0.94d