Some Thyrotropic Agents (Paperback) (ISBN-13: 9789283212799)

This volume evaluates carcinogenicity to humans of 19 chemicals that are carcinogenic to the thyroid follicular-cell epithelium in rodents. These included some so-called "anti-thyroid" drugs (methimazole, methylthiouracil, propylthiou-racil and thiouracil); some sedatives (doxylamine succinate and phenobarbital); and some other drugs including the systemic antifungal antibiotic griseofulvin, the diuretic spironolactone, and the antibacterial sulfa drugs sulfamethazine and sulfamethoxazole. Other chemicals are or have been used in agriculture as pesticides (amitrole, chlordane/heptachlor, hexachlo-robenzene and toxaphene), in foods and cosmetics (kojic acid), in hair dyes (2 4-diaminoanisole) or as industrial chemicals (N N'-diethylthiourea, ethylenethiourea and thiourea).

Author: The International Agency for Research on
ISBN-10: 9283212797
ISBN-13: 9789283212799
Publisher: World Health Organization
Language: English
Published: 11/01/2001
Pages: 763
Format: Paperback
Weight: 2.91lbs
Size: 10.00h x 7.00w x 1.54d