Stem Cells and Extracellular Matrices (Paperback) (ISBN-13: 9781615043767)

Stem cells have great potential in regenerative medicine and tissue injury. Regulation of stem cell homeostasis in a 3D microenvironment is controlled by the niche components that influence stem cell fate, regulation, and function. It is therefore necessary to understand the mechanisms of cell-cell interaction, molecular cross talk between stem cells and their extracellular matrix (ECM) environment. The adhesion molecules play a pivotal role in establishing the cell-cell contact and subsequent integration with the ECM. This understanding is the basis for establishing design criteria for biomimetic. The integrated approach by biologists, material science engineers, biomedical engineers, and clinicians is the key in the development of tissue engineered constructs for effective translation to clinics. Table of Contents: Abbreviations / Introduction to Stem Cell Biology and Niche Components / ECM-Structure and Organization / ECM Control, Regulation on Stem Cell Fate and Function / ECM and Stem Cell Cultures / Acknowledgments / Bibliography / Author Biography / Titles of Related Interest

Author: Lakshmi Kiran Chelluri
ISBN-10: 1615043764
ISBN-13: 9781615043767
Publisher: Morgan & Claypool
Language: English
Published: 04/12/2012
Pages: 84
Format: Paperback
Weight: 0.35lbs
Size: 9.25h x 7.50w x 0.17d