Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders (Hardcover) (ISBN-13: 9781493910557)

Recent studies show that changes in Glutamate/GABA synapses and related pathways may determine whether the synaptic plasticity that occurs as a response to stress is adaptive or maladaptive. Findings have shed new light on the mechanisms that determine the effects of stress on cognitive and affective function. Researchers have brought a wide range of techniques to bear on the study of this problem, including cutting-edge live imaging techniques, electrophysiology, glutamate release from isolated live synaptic terminals, development of transgenic and animal models and new behavioral methods. This book provides an overview of these recent findings and of the techniques used as well as a discussion of how the molecular, cellular, and functional effects of stress may trigger or precipitate neuropsychiatric disorders such as depression, schizophrenia, anxiety and PTSD.

Author: Maurizio Popoli
ISBN-10: 1493910558
ISBN-13: 9781493910557
Publisher: Springer
Language: English
Published: 07/28/2014
Pages: 355
Format: Hardcover
Weight: 1.53lbs
Size: 9.21h x 6.14w x 0.88d