T Cell Subsets: Cellular Selection, Commitment and Identity Volume 83 (Hardcover) (ISBN-13: 9780120224838)

This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular identity. Immunologists have a special interest in the mechanisms that allow selection of a T cell repertoire whose members integrate genetic information for T cell receptor, co-receptor and specialized immunologic function, since this process lies at the core of adaptive immunity.T Cell Subsets is a timely and invaluable review for immunologists, cell biologists hematologists and stem cell researchers

Author: Frederick W. Alt
ISBN-10: 0120224836
ISBN-13: 9780120224838
Publisher: Academic Press
Language: English
Published: 05/20/2004
Pages: 304
Format: Hardcover
Weight: 1.47lbs
Size: 9.24h x 5.94w x 0.81d