Tamoxifen: Pioneering Medicine in Breast Cancer (Hardcover) (ISBN-13: 9783034806633)

Discovery and Pharmacology of Nonsteroidal Estrogens and Antiestrogens.- Tamoxifen Goes Forward Alone.- Metabolites of Tamoxifen as the Basis of Drug Development.- Adjuvant Therapy - The Breakthrough.- The Wisconsin Story in the 1980's: Discovery of Target Site Specific Estrogen Action.- Carcinogenesis and Tamoxifen.- Chemoprevention: Cinderella waiting for the ball.- Tamoxifen and Raloxifene head to head: The STAR TRIAL.- Acquired resistance to Tamoxifen: back to the beginning.- The legacy of Tamoxifen.- Appendix: Four decades of discovery in breast cancer research and treatment - an interview with V. Craig Jordan by Marc Poirot.- Selected Awards that Recognize the Contribution of Tamoxifen and Raloxifene to Medicine.