TEXT BOOK OF MEDICINAL CHEMISTRY - l (Paperback) (ISBN-13: 9798895565001)

This book on Medicinal Chemistry provides a comprehensive exploration of the field, covering the history and development of medicinal chemistry and the importance of physicochemical properties such as ionization and solubility in drug action. It delves into the metabolism of drugs, categorizing them by phase reactions, and presents an in-depth analysis of drugs acting on the autonomic nervous system, including adrenergic and cholinergic neurotransmitters. Sympathomimetic agents and adrenergic antagonists are explained with detailed mechanisms of action, classification, and structure-activity relationships (SAR). The book also explores cholinergic blocking agents, sedatives, hypnotics, and antipsychotics, alongside detailed classifications of anticonvulsants, general anesthetics, and analgesics, with an emphasis on their mechanisms, uses, and SAR.