The Mechanism of Biochemical Action of Thyroid Hormones: Thyroid hormones in action (Paperback) (ISBN-13: 9781534949218)

Inosine mono phosphate (IMP) is a precursor of the two purine nucleotides, adenosine mono phosphate (AMP) and guanosine monophosphate (GMP): IMP -----adenylosuccinate ------AMP and IMP to xanthine monophosphate (XMP)---GMP. The reaction IMP----- adenylosuccinate is catalyzed by the enzyme synthetase which was purified and IMP---XMP is catalyzed by the enzyme IMP dehydrogenase which was purified also .Adenylosuccinate synthetase of rat liver is stimulated by L-T3 but not D-T4 and the effect of other analogues paralled their in vivo effects . The enzyme IMP dehydrogenase is inhibited by thyroid hormones, but not by D-T4, and also, the effects of other analogues paralled their in vivo effects.

Author: Sami a. Al-Mudhaffar Prof
ISBN-10: 1534949216
ISBN-13: 9781534949218
Publisher: Createspace Independent Publishing Platform
Language: English
Published: 06/27/2016
Pages: 164
Format: Paperback
Weight: 0.74lbs
Size: 10.00h x 7.99w x 0.35d