Vaccine Adjuvants (Hardcover) (ISBN-13: 9780896038929)

A cutting-edge review of the major research areas of adjuvant discovery, design, development, and use. The authors lay down a rational basis for vaccine adjuvant function and analyze a number of significantly distinct adjuvant-active molecules to illuminate the principles of their function and use. The focus is on specific receptor-ligand interactions, including the molecular features needed for a compound to possess adjuvant activity. The critical interface zone between the innate and adaptive immune systems is also analyzed to show how adjuvants exert their effects on T- and B-cell activation. Additional chapters address the possibility of tailoring adjuvants to yield optimally safe and effective responses.

Author: Charles J. Hackett
ISBN-10: 0896038920
ISBN-13: 9780896038929
Publisher: Humana
Language: English
Published: 12/01/2005
Pages: 284
Format: Hardcover
Weight: 1.31lbs
Size: 9.21h x 6.14w x 0.69d