Vaccine Adjuvants: Methods and Protocols (Hardcover) (ISBN-13: 9781493964437)

1. Overview of Vaccine Adjuvants: Introduction, History, and Current Status

Ruchi R. Shah, Kimberly J. Hassett, and Luis A. Brito

2. Development of the CpG Adjuvant 1018: A Case Study

John D. Campbell

3. Syntheses of Human TLR8-Specific Small-Molecule Agonists

Mallesh Beesu, Hari Prasad Kokatla, and Sunil A. David

4. Semisynthesis of Analogues of the Saponin Immunoadjuvant QS-21

Alberto Fern疣dez-Tejada, William E. Walkowicz, Derek S. Tan, and David Y. Gin

5. QS-21 Adjuvant: Laboratory-Scale Purification Method and Formulation into Liposomes

Livia Brunner, Christophe Barnier-Quer, and Nicolas Collin

6. Purification of an Immunoadjuvant Saponin Fraction from Quillaja brasiliensis Leaves by Reverse-Phase Silica Gel Chromatography

Anna C.A. Yendo, Fernanda de Costa, Carla Kauffmann, Juliane D. Fleck, Grace Gosmann, and Arthur G. Fett-Neto

7. Biosynthetic Approaches to Squalene Production: The Case of Yeast

Martin Valachovič and Ivan Hapala

8. In Silico Adjuvant Design and Validation

Matthew N. Davies, Helene Pere, Iris Bosschem, Freddy Haesebrouck, Bram Flahou, Eric Tartour, Darren R. Flower, David F. Tough, and Jagadeesh Bayry

9. Manufacturing Methods for Liposome Adjuvants

Yvonne Perrie, Elisabeth Kastner, Swapnil Khadke, Carla B. Roces, and Peter Stone

10. Synthesis of Lymph Node-Targeting Adjuvants

Melissa C. Hanson and Darrell J. Irvine

11. Preparing an Adjuvanted Thermoresponsive Gel Formulation for Sublingual Vaccination

Manjari Lal, Jessica White, and Changcheng Zhu

12. Manufacture of Oil-in-Water Emulsion Adjuvants

Jean Haensler

13. Methods to Prepare Aluminum Salt-Adjuvanted Vaccines

Sachin G. Thakkar and Zhengrong Cui

14. Production of Adjuvant-Loaded Biodegradable Particles for Use in Cancer Vaccines

Cristina Maria de Barros, Emad Ibrahim Wafa, Khanidtha Chitphet, Kawther Ahmed, Sean M Geary, and Aliasger K. Salem

15. Lyophilization of Adjuvanted Vaccines: Methods for Formulation of a Thermostable Freeze Dried Product

Michelle Y. Chan, Timothy S. Dutill, and Ryan M. Kramer

16. Stressed Stability Techniques for Adjuvant Formulations

Manvi Hasija, Anthony Sheung, Nausheen Rahman, and Salvador F. Ausar

17. Particle Sizing of Nanoparticle Adjuvant Formulations by Dynamic Light Scattering (DLS) and Nanoparticle Tracking Analysis (NTA)

Michelle Y. Chan, Quinton M. Dowling, Sandra J. Sivananthan, and Ryan M. Kramer

18. Quantification of Multiple Components of Complex Aluminum-Based

Author: Christopher B. Fox
ISBN-10: 1493964437
ISBN-13: 9781493964437
Publisher: Humana
Language: English
Published: 10/08/2016
Pages: 372
Format: Hardcover
Weight: 1.95lbs
Size: 10.00h x 7.00w x 0.88d